- GRB2-related adapter protein is a protein that in humans is encoded by the GRAP gene
GRAP Net worth 2024 (estimated)
| How much is GRAP worth? | Under review
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GRAP facts
- This gene encodes a member of the GRB2/Sem5 (C
- elegans homolog)/Drk (Drosophila homolog) family
- This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains
- The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein
- This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain
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